MacART is composed of a collaborative group of researchers, clinicians, and clinician-scientists who have come together to address the relative strengths and weaknesses faced by Autistic children and their families. MacART has attracted the participation of over 40 leading researchers from 14 departments and 5 research centres. MacART members are engaged in Autism-related research projects that range from the clinical, in which social communication skills are studied, to the biomedical, in which the gut/brain association is investigated, to the social/contextual, in which the relationship between child, family, school, and community are explored. MacART is also composed of top-level, experienced developmental pediatricians, psychiatrists, psychologists, and therapists at the Autism Spectrum Disorders Clinic, who diagnose over 100 children per year and provide care to 700 families in the greater Hamilton area. The proximity of academic researchers, clinicians, and clinician-scientists makes McMaster a unique place in Canada with the capacity to advance Autism care through meaningful research, using its combination of expertise and infrastructure.